The Sprague-Dawley (SD) is an outbred rat, and used extensively in the Discovery Services including Pharmacokinetics; extensively in the regulatory toxicological studies with various durations. Moreover, this strain is known to develop animal Pharmacological models of human conditions such as diabetes, obesity, cancer and cardiovascular diseases.
Colony health testing is performed according to FELASA recommendations.
• Used in virtually all disciplines of biomedical research including toxicology and pharmacology
• Excellent reproductive performance makes the SD rat a good model for generating timed pregnant females
*Now offered at the Excluded Flora health standard in addition to Murine Pathogen Free™ and Restricted Flora™. Excluded Flora and Restricted Flora™ SD rats are useful as health sentinels, clean fosters or where co-housed with immunodeficient/genetically modified models.
Origin:
The Sprague Dawley® outbred model was developed by Sprague Dawley, Inc. NIH received stock from Sprague Dawley, Inc in 1945. The rats are maintained as an outbred closed colony. Taconic received stock from the NIH Animal Genetic Resource in 1970. The rats were refreshed with NIH Genetic Resource stock in 1998.
Please contact us for pricing and availability of our Sprague Dawley in your region.